Tretinoin cream 0.05% in a 20g tube is a prescription-only topical medication used to treat acne vulgaris and fine wrinkles. It is a potent retinoid that is available from various brands, such as Obagi Medical and Retino A, and requires a doctor’s prescription for purchase and use. To use it, start with a small amount, applying a pea-sized amount to the affected area a few times a week and gradually increasing frequency as tolerated.

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